Glycogene Inc.

Products

Glycan modification

GlycoGenedeveloped a technology of glycan modification on proteins in vitro using human glycosyltransferases.
Also it will be available to introduce any glycosyltransferase into cells and modify glycan structure on a protein.
Glycan introduce and modification onto protein or peptide in vitro using recombinant human glycosyltransferases.
Introducing a proper glycosyltransferase gene into animal cells and it will be used for the preparation of a novel glycoprotein.

Recombinant human glycosyltransferases

GlycoGene successfully expressed most of recombinant human glycosyltransferases with tag for immobilizing enzymes on to resin which can be used for glycan synthesis or modification of glycoprotein or peptide. The number of enzymes will gradually increase and be available. Right now, it is 6 different enzymes are available.

Glycans

GlycoGene synthesize active oligosaccharides with use of recombinant human glycosyltransferases. We can provide glycan libraries as well as simple glycans. The glycan libraries are useful for analyzing of glycan binding profiles of proteins, such as receptors or cell surface lectin like molecules.
 - Human glycosyltransferases are used for synthesis of human active glycans
 - Any type of N-glycan and O-glycan will be synthesized and provided
 - O-glycan can be synthesized on a peptide

Glycan Structural analysis

GlycoGene provide structural analysis service of glycans on a glycoprotein as well as a simple glycan profiling of purified proteins, cells and tissues. We can analyze both N-and O-glycans on a proteins or cells / tissue.
 - Comprehensive profiling of glycans on glycoproteins by Mass Spec.
 - Comprehensive structural analysis by use of an advanced Mass Spec. analysis technology.